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Korean Journal of Obstetrics & Gynecology 2006;49(12):2473-2478.
Published online December 1, 2006.
Ovarian tissue cryopreservation and transplantation.
Ki Hyun Park, Byung Seok Lee, Da Jung Chung
Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea. kh8730@yumc.yonsei.ac.kr
Abstract
This review focuses on the current options for fertility preservation in patients with high risk of premature ovarian failure. Available cryopreservation options include embryo cryopreservation, oocyte cryopreservation, and ovarian tissue cryopreservation. Ovarian tissue cryopreservation and transplantation has been tried for some time in animals, but only recently successful pregnancy and livebirth in human has been reported. Options of developing follicles and restoring fertility after ovarian tissue cryopreservation are autotransplantation, xenotransplantation, and tissue culture. This review discusses the merits and faults of each option and future directions for developing and standardizing the ovarian tissue cryopreservation and transplantation procedure, systemically covering previously published data.
Key Words: Fertility preservation, Ovarian tissue cryopreservation and transplantation


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