A Case of Primary Signet Ring Cell Adenocarcinoma of the Uterine Cervix.

Lee, Jung Ju; Cha, Dong Soo; Han, Kyoung Hee; Chung, In Bai; Lee, Sang Young; Youm, Hyun Sik; Lee, Hyun Ju; Jung, Soon Hee

Case Report

Korean Journal of Obstetrics & Gynecology 2006;49(12):2626-2630.
Published online December 1, 2006.

A Case of Primary Signet Ring Cell Adenocarcinoma of the Uterine Cervix.

Jung Ju Lee, Dong Soo Cha, Kyoung Hee Han, In Bai Chung, Sang Young Lee, Hyun Sik Youm, Hyun Ju Lee, Soon Hee Jung

¹Department of Obstetrics and Gynecology, Wonju College of Medicine, Yonsei University, Wonju, Korea. dscha123@naver.com
²Department of Pathology, Wonju College of Medicine, Yonsei University, Wonju, Korea.

Abstract

Signet ring cell adenocarcinoma of the cervix is most commonly considered to be metastatic in origin. We describe one case of primary signet ring cell adenocarcinoma of the cervix occuring in 49-year-old patient. The lesion was located at the posterior lip of the cervix and about 3 cm in size. This case was parametrium thickening in pelvic examination and positive for HPV type 18. CCRT (concurrent chemoradiotherapy) was done for clinical FIGO stage II B adenocarcinoma of the cervix. The patient is alive for 6month since diagnosis and disappear lesion of the cervix. A upper gastroenteroscopy, colonoscopy, cystoscopy, intravenous pyelogram, abdominal pelvic CT, PET CT, mammogram were reported negative. Therefore we concluded this case for a primary cervical origin of signet ring cell adenocarcinoma of the uterine cervix.

Key Words: Primary Signet Ring Cell Adenocarcinoma, Cervical adenocarcinoma