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Korean Journal of Obstetrics & Gynecology 2007;50(1):111-116.
Published online January 1, 2007.
Spontaneous regression of the mild cervical dysplasia and its related factors.
Yea Sung Cho, Hyun Joo Jung, Sun Rye Jeon, Hye Jin Cho, Ga Hyun Son, Eun Kyoung Choi
1Department of Obstetrics and Gynecology, National Health Insurance Cooperation Ilsan Hospital, Koyang, Korea. szerying@hotmail.com
2Department of Obstetrics and Gynecology, College of Medicine, Yonsei University, Seoul, Korea.
The aim of this study was to assess the regression rate of the mild cervical dysplasia and to examine the factors associated with the regression. METHODS: One hundred and nine women pathologically confirmed with mild cervical dysplasia were recruited into this study. They were followed up by cytology, colposcopy and human papillomavirus DNA test at 3 months and 6 months after the diagnosis. The participants filled out a questionnaire on their demographic characteristics and sexual history. RESULTS: The rate of spontaneous regression for the mild cervical dysplasia was 59.6%(65/109). Multivariate analysis showed that initial ASCUS cytology, negative HPV status, non-smoker, condom user and age under 40 years old were associated with higher regression rate. CONCLUSIONS: The rate of regression for mild cervical dysplasia seen in our study was particularly higher than the result in previous study. Therefore, we recommend that the patients with mild cervical dysplasia can be followed up by cytology and HPV DNA study without any intervention, especially in young patients. Initial ASCUS cytology, negative HPV status, non-smoker, condom user and age under 40 years old were good related factors for regression.
Key Words: Regression, Mild cervical dysplasia, Related factors
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