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Korean Journal of Obstetrics & Gynecology 2007;50(3):539-544.
Published online March 1, 2007.
A case of clear cell carcinoma that is unrelated to diethystilbestrol of the uterine cervix.
Su Mi Na, Seong Hwan Oh, Heung Gon Kim, Hyung Bae Moon
1Department of Obstetrics and Gynecology, College of Medicine, University of Wonkwang Medical School, Iksan, Korea. h1gkim@chollian.net
2Department of Pathology, College of Medicine, University of Wonkwang Medical School, Iksan, Korea.
Clear cell carcinoma of the uterine cervix is rare type of the uterine cervical adenocarcinoma. Although uterine cervical adenocarcinomas presently represent 20% to 30% of cervical cancers in the industrialized countries, the clear cell carcinoma of uterine cervix is very rare malignancy that accounts for 4% to 9% of the adenocarcinoma of uterine cervix. This malignancy occurs in two distinct age groups; those younger than 24 years and those older than 45 years. In younger patients, most of these malignancies are mainly related to prenatal diethylstilbestrol (DES) exposure, but older patients are unrelated to in utero DES-exposure. We experienced a case of clear cell carcinoma of the uterine cervix of 34 years old housewife who was not related to prenatal DES-exposure. We presented a case with a brief review of related literatures.
Key Words: Clear cell carcinoma, Uterine cervical adenocarcinoma, DES

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