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Korean Journal of Obstetrics & Gynecology 2007;50(4):666-672.
Published online April 1, 2007.
Characteristics of dietary pattern and tissue mineral in premenstrual syndrome patients.
Hyun Hee Cho, Jae Eun Jung, Ju Yong Lee, Mee Ran Kim, Young Ok Lew, Yong Taik Lim, Eun Jung Kim, Jin Hong Kim
1Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, Korea. drrabbit@catholic.ac.kr
2Department of Obstetrics and Gynecology, College of Medicine, University of Wonkwang Medical School, Iksan, Korea.
About 80% of premenopausal women experience premenstrual syndrome (PMS), but the definite etiology or effective treatment is still under the investigation. In this study, serum and tissue mineral analysis, which are essential for biosynthesis and secretory regulation of neurotransmitters, We evaluate what kind of changes in mineral levels is correlated to the presence of PMS. This study also include the approaches that entail changes to diet and lifestyle so that symptoms of premenstrual disorders can be alleviated. 61 women who were recruited on volunteer basis and completed Modified Moss Menstrual Distress Questionnaire (MMDQ) and devided into 2 groups, scored less than 10 points, as control group, and women scored higher than 11 points, as PMS group. They were asked to fill out questionnaires about their diet patterns and submitted to tissue mineral and serum analysis to evaluate the levels of Ca, Mg, Na, K, Cu, and Zn. In the control group, serum Mg and Zn were relatively high but within normal reference range, but showed high level of Mg and Zn in tissue. For Mini Dietary Assessment Index (MDAI), the score of control group was 33.8 and that of PMS group 19.7, showed statistical significance (P<0.05). The score of daily calcium-taking group was 21.6+/-3.7 whereas that of seldom calcium-taking group was 39.6+/-6.2 (P<0.05). The score of daily magnesium-taking group was 9.75+/-2.7 whereas that of seldom magnesium-taking group was 26.0+/-4.9 (P<0.05). In this study, we conclude the importance of dietary and lifestyle modifications could prevent and treat symptoms of PMS and minerals had significant roles of regulating PMS especially Ca, Mg and Zn. Further studies about roles of these minerals and possible therapeutic applications using minerals in PMS are needed.
Key Words: Premenstural syndrome, Zinc, Magnesium, Calcium

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