Recurrent aggressive angiomyxoma of vulva: A case report.

An, So Jung; Park, Noh Hyun; Park, Young Soo; Won, Mi Youn; Kim, Jae Weon; Song, Yong Sang; Kang, Soon Beom; Lee, Hyo Pyo

Case Report

Korean Journal of Obstetrics & Gynecology 2007;50(8):1166-1170.
Published online August 1, 2007.

Recurrent aggressive angiomyxoma of vulva: A case report.

So Jung An, Noh Hyun Park, Young Soo Park, Mi Youn Won, Jae Weon Kim, Yong Sang Song, Soon Beom Kang, Hyo Pyo Lee

Department of Obstetrics and Gynecology, College of Medicine Seoul National University, Seoul, Korea. pnhkhr@snu.ac.kr

Abstract

Aggressive angiomyxoma (AAM) is a rare soft tissue tumor composed of scattered spindle cells and abundant vessels embedded in a myxoid matrix. It is a benign slow growing tumor, but locally infiltrative and have a propensity of recurrence. We described the case of a recurrent aggressive angiomyxoma of vulva in a 47-year old female patient. She had a history of vulvar excision at local clinic 2-years ago, and visited our institute with a complaint of pain associated vulvar mass. Wide local excision with postoperative adjuvant GnRH agonist therapy was done according to pathologic report which revealed positive resection margin with estrogen/progesterone receptors positive. She is now free of disease during 15 months of follow up. We report the case with a brief review of the literature.

Key Words: Angiomyxoma, Vulva