A case of sarcoma arising in ovarian mature cystic teratoma.

Park, Mi Sun; Suh, Min Jung; Choi, Joo Hyuk; Yoon, Joo Hee; Park, Dong Choon

Case Report

Korean Journal of Obstetrics & Gynecology 2007;50(10):1414-1421.
Published online October 1, 2007.

A case of sarcoma arising in ovarian mature cystic teratoma.

Mi Sun Park, Min Jung Suh, Joo Hyuk Choi, Joo Hee Yoon, Dong Choon Park

Department of Obstetrics and Gynecology, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea. dcpark@catholic.ac.kr

Abstract

Benign cystic teratoma is the common ovarian tumor, and the incidence reported about 20%. Between 1 and 2% of mature cystic teratomas undergo malignant trasformation. This occurs most frequently in postmenopausal women, who account for only 10% of mature cystic teratomas. Among the malignant transformations, squamous cell carcinoma is the most common type (over 75%), and adenocarcinoma, undifferentiated carcinoma, malignant melanoma, thyroid adenocarcinoma, and sarcoma have been reported in the literature. Because of its rarity, the clinico-pathologic characteristics are not well established, and there is no consensus on optimal therapy. There is also no consensus regarding the efficacy of postoperative therapy. We experienced a case of sarcoma of the ovary arising in mature cystic teratoma, which is presented with a brief review of literature.

Key Words: Ovarian sarcoma, Mature cystic teratoma, Malignant transformation