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Korean Journal of Obstetrics & Gynecology 2007;50(11):1558-1562.
Published online November 1, 2007.
Two cases of spontaneous pregnancy in women with premature ovarian failure: Case report.
Soo Kyung Lee, Bo Sun Joo, Sung Eun Moon, Sang Kap Kim, Ja Sung Koo, Hwa Sook Moon
1Department of Obstetrics and Gynecology, Good Moonhwa Hospital, Busan, Korea. moonhwas@moonhwa.or.kr
2Center for Reproductive Medicine, Good Moonhwa Hospital, Busan, Korea.
3Planned Population Federation of Korea.
Premature ovarian failure (POF) is a syndrome defined as hypergonadotropic hypogonadism associated with amenorrhea, oligomenorrhea or other forms of menstrual irregularity for at least 3 consecutive months before the age of 40. The management of POF is approached by HRT, emotional support and infertility treatment. Women with premature ovarian failure who desire to become pregnant are best treated by assisted reproductive technology with donor oocyte. However, POF has the possibility of a 5-10% spontaneous pregnancy. The physician should recommend the patient to consult with their physician if they have any symptoms of pregnancy or no withdrawal bleeding after HRT. Therefore we report two cases of spontaneous pregnancies in women with premature ovarian failure.
Key Words: Premature ovarian failure, Spontaneous pregnancy

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