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Korean Journal of Obstetrics & Gynecology 2008;51(11):1396-1401.
Published online November 1, 2008.
A case of aggressive angiomyxoma of the vulva.
Byung Joon Park, Yong Wook Kim, Tae Eung Kim, Lee So Maeng
1Department of Obstetrics and Gynecology, Incheon st. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea. tekim@catholic.ac.kr
2Department of Pathology, Incheon st. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
Abstract
Aggressive angiomyxoma is an uncommon soft-tissue neoplasm which affects the pelvis and genital organs of the young female predominantly. This tumor has a high tendency of local recurrence, but it usually does not develop metastasis. Although surgical excision with wide tumor-free margins may be necessary to obtain a complete cure, some of patients experience local recurrences. Many of the tumors are estrogen receptor (ER) and progesterone receptor (PR) positive and medical therapy with gonadotropin-releasing hormone (GnRH) agonists showed to be effective in a few cases. We present a case of 29-years-old women who has aggressive angiomyxoma which was misdiagnosed as bartholin duct cyst. She was treated by wide local excision with postoperative adjuvant GnRH agonist therapy for 3 months. She is now free of disease during 9 months of follow up. We have described this case with the brief of literature.
Key Words: Aggressive angiomyxoma, Vulva


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