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Korean Journal of Obstetrics & Gynecology 2009;52(2):212-219.
Published online February 1, 2009.
Clinicopathologic characteristics and prognostic factors of primary peritoneal carcinoma.
Hee Joung Woo, Sang Heon Kim, Kidong Kim, Sang Il Park, Yong Jung Song, Beob Jong Kim, Moon Hong Kim, Seok Cheol Choi, Sang Young Ryu, Eui Don Lee, Kyung Hee Lee
1Department of Obstetrics & Gynecology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea. beob@kcch.re.kr
2Department of Obstetrics & Gynecology, National Cancer Center, Gyeonggi, Korea.
The objective of this study was to examine the clinicopathologic characteristics and prognostic factors of primary peritoneal carcinoma (PPC). METHODS: Clinicopathologic variables were obtained by examining the medical records of patients with PPC who were diagnosed and treated at our institute, between January 1996 and December 2005. To find prognostic factors, the association of clinicopathologic variables with survival was evaluated by univariate and multivariate analysis. RESULTS: All patients had advanced-stage tumors. Residual tumor was smaller than 1 cm in 12 patients and was equal or larger than 1 cm in nine patients. The response rate to adjuvant chemotherapy was 47.6%. The median progression-free survival was eight months (range 1~95) and the median overall survival was 14 months (range 1~99). In univariate analysis, stage, the response to adjuvant chemotherapy, and neoadjuvant chemotherapy were associated with survival. However, in multivariate analysis, no variables were associated with survival. CONCLUSION: In spite of aggressive treatments, patients with PPC had poor prognosis. No prognostic factors were identified in this study.
Key Words: Primary peritoneal carcinoma, Overall survival, Prognostic factor

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