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Korean Journal of Obstetrics & Gynecology 2009;52(4):391-399.
Published online April 1, 2009.
Ischemic perinatal stroke.
Cheong Rae Roh
Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. crroh@skku.edu
Abstract
Ischemic perinatal stroke occurring around the time of delivery is increasingly recognized as a cause of neurological disability in children. Surprisingly, the incidence of arterial infarction in neonates is as high as the annual incidence of large-vessel ischemic stroke in adults. Neonatal seizure is the most common clinical finding that triggers assessment. In other children, ischemic perinatal stroke is recognized only retrospectively with emerging hemiparesis or seizures after the early months of life. The outcome of ischemic perinatal stroke is variable and depends on severity, anatomic localization and other factors not yet well characterized. There is much to be learned about the natural history of ischemic perinatal stroke and there is as yet no evidence-based strategy for prevention or treatment. The incidence, clinical presentation, pathogenesis, risk factors and outcomes of this disorder are reviewed.
Key Words: Ischemic perinatal stroke, Seizure
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