Korean J Obstet Gynecol Search

CLOSE


Korean Journal of Obstetrics & Gynecology 2009;52(8):883-888.
Published online August 1, 2009.
A case of unusual premature ovarian failure with 46,X,dup(Xq).
Hye Sun Hyeon, Bo Ra Park, Yun Sook Kim, Seong Taek Mun, Seob Jeon, Youn Seok Choi, Dong Han Bae
Department of Obstetrics and Gynecology, University of Soonchunhyang, College of Medicine, Soonchunhyang University Chunan Hospital, Chunan, Korea. drsook@schca.ac.kr
Abstract
Premature ovarian failure (POF) is defined as the complete cessation of menses less than 40 years of age. The criteria are more than four months of amenorrhea, with serum follicle stimulating hormone value of >40 mIU/mL and the frequency of POF is about 1% of all women. Although the etiologies of POF remain unknown, suggested factors are genetic, autoimmune, chemotherapy, radiotherapy and environmental toxins. The cytogenetic abnormalities predominantly concern the X chromosome, including Turner syndrome, Fragile X syndrome and deletion, translocation, or duplication of X chromosome. We report a very rare case of premature ovarian failure with the following karyotype: 46,X,dup(Xq), and report it with a brief review of literature.
Key Words: Premature ovarian failure (POF), X chromosome, Duplication


ABOUT
ARTICLE & TOPICS
Article category

Browse all articles >

Topics

Browse all articles >

BROWSE ARTICLES
POLICY
FOR CONTRIBUTORS
Editorial Office
4th Floor, 36 Gangnam-daero 132-gil, Gangnam-gu, Seoul 06044, Korea
Tel: +82-2-3445-2382    Fax: +82-2-3445-2440    E-mail: journal@ogscience.org                

Copyright © 2021 by Korean Society of Obstetrics and Gynecology.

Developed in M2PI

Close layer
prev next