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Obstet Gynecol Sci > Volume 52(10); 2009 > Article
Korean Journal of Obstetrics & Gynecology 2009;52(10):1051-1055.
Published online October 1, 2009.
Two cases of primary malignant lymphoma of the uterine cervix.
Sun Ok Lim, Eun Young Key, Duck Yeong Ro, Byung Joon Park, Yong Wook Kim, Tae Eung Kim, Jae Keun Jung, Chi Wha Han, An Hi Lee
1Department of Obstetrics and Gynecology, The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Korea. duckyeong20@yahoo.co.kr
2Department of Hemato-Oncology, The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Korea.
3Department of Pathology, The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Korea.
Abstract
Primary malignant lymphoma of the uterine cervix is very rare. Lymphomas account for 3.5% of all malignant tumors in the females. Approximately, 25% of all malignant lymphomas arise from extranodal sites, most frequently from gastrointestinal tract and skin. Although the incidence of systemic non-Hodgkin's lymphoma (NHL) and extranodal NHL has increased in recent decades, only 1 to 1.5% arises from female genital tract. Primary pelvic sites include ovary, which is the most common site, uterine corpus, cervix, vagina, and vulva. Primary cervical lymphomas account for 0.12~0.6% of all extranodal lymphomas. However, there is still no consensus on the management of cervical lymphomas due to low incidence of the disease and limited experience in the literature. We experienced two cases of primary malignant lymphoma of the uterine cervix. A 41-year-old woman, Ann Arbor stage IE, was treated with laparoscopically assisted vaginal hysterectomy and both salpingo-oophorectomy and 4 cycles chemotherapy. A second case was a 73-year-old postmenopausal woman, Ann Arbor stage III, received five courses chemotherapy without any surgery. In this article, two cases of uterine cervical lymphoma are presented with a review of the available literature.
Key Words: Primary malignant Lymphoma, Uterine cervix
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