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Korean Journal of Obstetrics & Gynecology 2009;52(12):1326-1330.
Published online December 1, 2009.
A case of squamous cell carcinoma arising from ovarian mature cystic teratoma treated with adjuvant chemoradiation.
Jeong Shin Park, Suk Bong Ko, Tae Sung Lee, Ju Hyun Kim
Department of Obstetrics and Gynecology, School of Medicine, Catholic University of Daegu, Daegu, Korea. drkjh@cu.ac.kr
Malignant transformation of mature cystic teratoma is rare and difficult to diagnose preoperatively. Therefore, in the suspected case considering the age, tumor size and imaging findings, it is important to diagnose intraoperatively through a frozen section biopsy. It is clear that aggressive optimal surgical resection should be done in the squamous cell carcinoma arising from mature cystic teratoma. However it is controversy what postoperative adjuvant therapy is optimal in the locally advanced case because of its rarity. We report a case of a 59-year-old woman in the menopause with locally advanced squamous cell carcinoma arising from left ovarian mature cystic teratoma treated with optimal cytoreductive surgery followed by concurrent chemoradiation.
Key Words: Mature cystic teratoma, Malignant transformation, Squamous cell carcinoma

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