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Fertility-sparing treatment in early endometrial cancer: current state and future strategies
Andreas Obermair, Eva Baxter, Donal J. Brennan, Jessica N. McAlpine, Jennifer J. Muellerer, Frédéric Amant, Mignon D. J. M. van Gent, Robert L. Coleman, Shannon N. Westin, Melinda S. Yates, Camilla Krakstad, Monika Janda
Obstet Gynecol Sci. 2020;63(4):417-431. Published online 2020 Jul 8 DOI: https://doi.org/10.5468/ogs.19169
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Biology.2024; 13(8): 584. CrossRef Application and evaluation of minimally invasive surgical treatment options for early endometrial cancer
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Trials.2024;[Epub] CrossRef Uterine-Conserving Treatment Options for Atypical Endometrial Hyperplasia and Early Endometrial Cancer
Naomi N. Adjei, Mikayla Borthwick Bowen, Roni Nitecki Wilke, Melinda S. Yates, Shannon N. Westin
Current Oncology Reports.2024; 26(11): 1367. CrossRef Weight-Loss and Metformin-Use Improve the Reversal Rate in Patients with Endometrial Hyperplasia
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International Journal of Women's Health.2024; Volume 16: 1815. CrossRef State of the art endocrine treatments for patients diagnosed with endometrial cancer in 2025
Fernanda B. Musa, Kathleen N. Moore, Vivek Podder, Brian M. Slomovitz
Current Opinion in Obstetrics & Gynecology.2024;[Epub] CrossRef ESGO/ESHRE/ESGE Guidelines for the fertility-sparing treatment of patients with endometrial carcinoma
A Rodolakis, G Scambia, F Planchamp, M Acien, A Di Spiezio Sardo, M Farrugia, M Grynberg, M Pakiž, K Pavlakis, N Vermeulen, G Zannoni, I Zapardiel, K.L. Tryde Macklon
Facts, Views and Vision in ObGyn.2023;[Epub] CrossRef Using menopausal hormone therapy after a cancer diagnosis in Ireland
Fionán Donohoe, Yvonne O’Meara, Aidin Roberts, Louise Comerford, Catherine M. Kelly, Janice M. Walshe, Deirdre Lundy, Martha Hickey, Donal J. Brennan
Irish Journal of Medical Science (1971 -).2023; 192(1): 45. CrossRef Disparities in Fertility-Sparing Treatment and Use of Assisted Reproductive Technology After a Diagnosis of Cervical, Ovarian, or Endometrial Cancer
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International Journal of Gynecological Cancer.2023; 33(2): 208. CrossRef Human chorionic gonadotropin expression in endometrial hyperplasia and endometrial carcinoma: could it be a new marker?
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Gynecologic Oncology.2023; 179: 180. CrossRef Organ preservation treatment of patients with atypical hyperplasia and endometrial cancer: current trends
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Academic Radiology.2022; 29(8): e119. CrossRef British Gynaecological Cancer Society (BGCS) uterine cancer guidelines: Recommendations for practice
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Cancers.2022; 14(9): 2170. CrossRef Fertility after Cancer: Risks and Successes
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Bioengineering.2022; 9(5): 226. CrossRef Demographic shifts associated with implementation of evidence-based guidelines for ovarian conservation in patients with endometrioid endometrial cancer
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Obstetrics & Gynecology Science.2022; 65(4): 376. CrossRef Fertility Preservation in Endometrial Cancer: Current Knowledge and Practice
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Journal of Obstetrics, Gynecology and Cancer Research.2022; 7(5): 362. CrossRef Levonorgestrel-releasing intrauterine device plus metformin, or megestrol acetate plus metformin for fertility-sparing treatment of atypical endometrial hyperplasia and early endometrial carcinoma: a prospective, randomized, blind-endpoint design trial pr
Xin Zhao, Jumin Niu, Cong Shi, Zhihui Liu
Reproductive Health.2022;[Epub] CrossRef ESGO/ESHRE/ESGE Guidelines for the fertility-sparing treatment of patients with endometrial carcinoma,
Alexandros Rodolakis, Giovanni Scambia, François Planchamp, Maribel Acien, Attilio Di Spiezio Sardo, Martin Farrugia, Michael Grynberg, Maja Pakiz, Kitty Pavlakis, Nathalie Vermeulen, Gianfranco Zannoni, Ignacio Zapardiel, Kirsten Louise Tryde Macklon
Human Reproduction Open.2022;[Epub] CrossRef Role of hysteroscopy during conservative management of atypical endometrial hyperplasia and early-stage endometrial cancer in patients who desire pregnancy
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International Journal of Gynecological Cancer.2021; 31(3): 352. CrossRef Manejo terapéutico quirúrgico para la preservación de la fertilidad en las pacientes con cáncer de cérvix, endometrio y ovario
A. Redondo Villatoro, M. Moreno López, M. Pantoja Garrido
Clínica e Investigación en Ginecología y Obstetricia.2021; 48(3): 100656. CrossRef Fertility-Sparing Methods in Adolescents Affected by Endometrial Cancer: A Comprehensive Review
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Journal of Clinical Medicine.2021; 10(5): 1020. CrossRef Anaesthetic considerations for fertility‐sparing surgery and uterine transplantation
L. S. Kasaven, B. P. Jones, R. Keays, S. Saso
Anaesthesia.2021; 76(S4): 46. CrossRef Practical issues and research trends of oncofertility in gynecologic cancer
Jeong-Yeol Park
Korean Journal of Women Health Nursing.2021; 27(2): 64. CrossRef Fertility-sparing approach for endometrial cancer: the role of office hysteroscopy
José Carugno, Adriana Wong
Minimally Invasive Therapy & Allied Technologies.2021; 30(5): 296. CrossRef Novel polymer-based system for intrauterine delivery of everolimus for anti-cancer applications
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Cancer Prevention Research.2021; 14(11): 1041. CrossRef Fertility Sparing Treatments in Endometrial Cancer Patients: The Potential Role of the New Molecular Classification
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International Journal of Molecular Sciences.2021; 22(22): 12248. CrossRef Conservative Surgery in Endometrial Cancer
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Journal of Clinical Medicine.2021; 11(1): 183. CrossRef Comments on: Fertility-sparing treatment for intramucous, moderately differentiated, endometrioid endometrial cancer: a Gynecologic Cancer Inter-Group (GCIG) study
Jeong-Yeol Park
Journal of Gynecologic Oncology.2020;[Epub] CrossRef Fertility preservation in women with endometrial cancer
Helena Bralo, Maria Roethlisberger, Kazem Nouri
memo - Magazine of European Medical Oncology.2020; 13(4): 421. CrossRef
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