Transplacental Fetal Therapy for a Case of Fetal Supraventricular Tachycardia which Caused Fetal Hydrops.

Roh, Cheong Rae; Kang, E Suk; Moon, Jong Taek; Yang, Soon Ha; Chung, Jae Hyun; Lee, Heung Jae; Lee, Je Ho

Original Article

Korean Journal of Obstetrics & Gynecology 1997;40(10):2145-2152.
Published online January 1, 2001.

Transplacental Fetal Therapy for a Case of Fetal Supraventricular Tachycardia which Caused Fetal Hydrops.

Cheong Rae Roh, E Suk Kang, Jong Taek Moon, Soon Ha Yang, Jae Hyun Chung, Heung Jae Lee, Je Ho Lee

¹Department of Obstetrics and Gynecology, Samsung Seoul Hospital, Samsung Medical Center, Seoul, Korea.
²Department of Pediatrics, Samsung Seoul Hospital, Samsung Medical Center, Seoul, Korea.

Abstract

A case of fetal supraventricular tachycardia which caused fetal hydrops was diagnosed at 29 weeks of gestation by fetal echocardiography. Transplacental fetal therapy with ma-ternal intravenous digoxin administration resulted in restoration of normal fetal sinus rhythm and disappearance of fetal hydrops on 7th day after initiation of treatment when the mat-ernal serum digoxin level was 2.11 ng/mL. The fetus showed normal sinus rhythm when evaluated by fetal echocardiography during the remainder of pregnancy with maternal oral digoxin maintenence. At birth, the infant did not show any cardiac arrhythmia and hydropic appearance.

Key Words: Fetal supraventricular tachycardia, fetal hydrops, fetal echocardiography, transpla-cental fetal therapy