A Case Of Acute Misoprostol Toxicity.

Kim, U Chul; Yim, Soo Bin; Park, Woon Ho; Jung, Hae Ryon; Lee, Ho; Lee, Jung Eun; Lee, Ji Young; Lee, Woo Young

Case Report

Korean Journal of Obstetrics & Gynecology 2002;45(8):1380-1384.
Published online August 1, 2002.

A Case Of Acute Misoprostol Toxicity.

U Chul Kim, Soo Bin Yim, Woon Ho Park, Hae Ryon Jung, Ho Lee, Jung Eun Lee, Ji Young Lee, Woo Young Lee

Department of Obstetrics and Gynecology, College of Medicine, Inha University, Inha Hospital, Kyunggi, Korea.

Abstract

Misoprostol (Cytotec) is a prostaglandin E1 analog used in prevention of nonsteroidal anti-inflammatory drugs induced gastric ulcer and has a uterotonic effect. It has been used to terminate pregnancy at any stage by promoting uterine contractions and for ripening the cervix before induced labor or abortion. Recently, it is known to reduce postpartum hemorrhage. Very little experience has been reported acute misoprostol toxicity in contrast with its usages. We have experienced a case of acute toxicity of misoprostol used for management of postpartum hemorrhage. We report this case with a review of literatures.

Key Words: 4Misoprostol, toxicity, postpartum hemorrhage