A Case of Myasthenia Gravis in Pregnancy.

Kang, Ji Hoon; Han, Kyun; Song, Ji Hyun; Choi, Jae Sung

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Korean Journal of Obstetrics & Gynecology 2003;46(5):1064-1068.
Published online May 1, 2003.

A Case of Myasthenia Gravis in Pregnancy.

Ji Hoon Kang, Kyun Han, Ji Hyun Song, Jae Sung Choi

Department of Obstetrics and Gynecology, Sun General Hospital, Daejeon, Korea.

Abstract

Myasthenia gravis is a autoimmune neuromuscular disorder characterized by weakness and fatigability of skeletal muscles. The underlying defect is a decrease in the number of available acetylcholine receptors at neuromuscular junction due to an antibody-mediated autoimmune attacks. The course of myasthenia gravis during pregnancy is not predictable. We experienced a patient of myasthenia gravis associated with pregnancy who underwent cesarean section and transient neonatal myasthenia gravis of the newborn. We present this case with brief review of the concerned literatures.

Key Words: Myasthenia gravis, Pregnancy, Transient neonatal myasthenia gravis

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