The Value of Transvaginal Ultrasonographic Measurement of Cervical Length for Prediction of Preterm Delivery in Patients with Preterm Labor. |
Su Ran Choi, Soon Ha Yang, Ji Soo Lee, Yong Soo Seo, Jong Hwa Kim |
Department of Obstetrics and Gynecology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea. |
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Abstract |
OBJECTIVE The aim of this study is to evaluate the value of vaginal ultrasonographic cervical length in prediction of preterm delivery in patients with preterm labor. METHODS: One-hundred twenty-nine women in preterm labor at 24-34 weeks of gestation were studied retrospectively. Transvaginal ultrasonography for measurement of cervical length was performed at the time of admission. Receiver-operating characteristic (ROC) curve analysis, partial correlation coefficient, and multiple logistic regression analysis were used for statistical analysis. RESULTS: The mean gestational age at admission was 30.2 +/- 2.5 weeks and the mean gestational age at delivery was 35.7 +/- 3.9 weeks. The median admission-to-delivery interval was 864 hours (24-2616). ROC curve analysis showed a significant relationship between cervical length and preterm delivery (area under the curve=0.82, p<0.001). The diagnostic indices of cervical length (cut-off value 2.5 cm) by ROC curve were sensitivity of 86%, specificity of 64%, and positive and negative predictive value of 54% and 90%. Multiple logistic regression analysis indicated that cervical length was an independent predictor of preterm delivery after adjustment of confounding factors (x2=0.326, p<0.01). Admission-to-delivery interval in patients with cervical length >or=2.5 cm was significantly shorter than that in patients with cervical length >2.5 cm. CONCLUSION: Transvaginal ultrasonographic measurement of cervical length is a useful predictor of preterm delivery in patients with preterm labor and intact membranes. |
Key Words:
Transvaginal ultrasonography, Cervical length, Preterm delivery, Preterm labor |
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