A Case of Sertoli-Leydig Cell Tumor.

Cho, Young Seog; Shin, Kyung Jae; Kim, Sang Myung; Kim, Ki Hyun

Case Report

Korean Journal of Obstetrics & Gynecology 2003;46(12):2524-2527.
Published online December 1, 2003.

A Case of Sertoli-Leydig Cell Tumor.

Young Seog Cho, Kyung Jae Shin, Sang Myung Kim, Ki Hyun Kim

Department of Obstetrics and Gynecology, Seoul Red Cross Hospital, Seoul, Korea.

Abstract

The Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0.5% of all primary ovarian neoplasm. The majority of these tumors are benign and almost all are localized unilaterally. Sertoli-Leydig cell tumors occur predominantly in the second and third decades, rarely before puberty or after the menopause. In 40-50% of the patients, the presenting symptoms relate to clinical signs of androgenic activity. While most of the remainder are non-specific abdominal symptoms. Prognosis is generally favorable with 5-year survival rate of 70-90%. Recurrence is rare. Treatment varies with patient age, tumor stage, and differentiation from unilateral salpingo-oophorectomy and total hysterectomy concomitant with pelvic lymph node dissection. We have experienced a case of postmenopausal Sertoli-Leydig cell tumor with vaginal bleeding and so we present it with brief review of literature.

Key Words: Sertoli-Leydig cell tumor, Sex cord stromal cell tumor, Vaginal bleeding