Trousseau's syndrome in association with ovarian clear cell carcinoma.

Kwon, Ji Young; Han, Chan Hui; Cho, Hyun Jung; Choi, Ju Hyouk; Kim, Ju Hwan; Han, Gu Taek; Ryu, Ki Sung

Case Report

Korean Journal of Obstetrics & Gynecology 2005;48(8):1976-1981.
Published online August 1, 2005.

Trousseau's syndrome in association with ovarian clear cell carcinoma.

Ji Young Kwon, Chan Hui Han, Hyun Jung Cho, Ju Hyouk Choi, Ju Hwan Kim, Gu Taek Han, Ki Sung Ryu

Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, Korea. ryuks@catholic.ac.kr

Abstract

The association of neoplastic disease and thromboembolic disorder was first recognized by Trousseau in 1865. Since then, thromboembolic events have often been reported in a variety of malignant conditions. Recently, we experienced an unusual case of a 67-year-old ovarian cancer patient with extensive thromboembolic events involving lung, brain, extremity and abdominal cavity. In this report, we describe a systemic coagulopathy fluctuating in accordance with anticoagulant therapy, and have special regard for a role of anticoagulants for the treatment of this syndrome.

Key Words: Ovarian cancer, Trousseau's syndrome, Thromboembolism, Anticoagulant therapy