A Case of Partial Hydatidiform Mole with a Coexistent Live Fetus.

An, Kwang Jun; Yoon, Douk Hun; Ryu, Joo Yuen; Kim, Hang Jin; Park, Hak Youl; Son, Kyung Rak

Case Report

Korean Journal of Obstetrics & Gynecology 2006;49(2):477-482.
Published online February 1, 2006.

A Case of Partial Hydatidiform Mole with a Coexistent Live Fetus.

Kwang Jun An, Douk Hun Yoon, Joo Yuen Ryu, Hang Jin Kim, Hak Youl Park, Kyung Rak Son

¹Department of Obstetrics and Gynecology, Daegu Fatima Hospital, Daegu, Korea. Jamesphy@hanmail.net
²Department of Pathology, Daegu Fatima Hospital, Daegu, Korea.

Abstract

Hydatidiform moles are generally separated into two classifications. Complete hydatidiform moles are characterized by cystic swelling of all villi, often pronounced trophoblastic hyperplasia, lack of fetal parts, all 46 chromosomes of paternal origin, and a major risk for persistent trophoblastic tumor. Partial hydatidiform moles appear to be a milder version of complete moles with both normal and cystic villi, focal trophoblastic hyperplsia, a fetus or indication of previous fetal existence, 69 chromosomes with a maternal contribution, and a malignant potential less than described for complete moles. Hydatidiform mole with coexistent fetus is a very rare phenomenon, with an estimated incidence of 0.005 to 0.01 percent of all pregnancies. Due to advances in cytogenetics and ultrasonography, now permit the diagnosis of this pregnancy antenatally. However this unusual pregnancy has the risks of malignant change and severe medical complications, so it is a dilemma to decide continuation or termination of pregnancy. We experienced a case of partial hydatidiform mole with coexistent live fetus, which was diagnosed by ultrasonography at 12 gestational weeks, and confirmed normal karyotype (diploid) of the coexistent fetus. A brief reviews of related literature was done.

Key Words: Complete mole, Patial mole, Coexisting fetus, Diploid