Two Cases of Pregnancies Complicated with Central Diabetes Insipidus.

Lee, Seung Ho; Kim, Jin A; Kim, Yong Jin; Lee, Yu Kyung; Hwang, Kyu Ri; Shim, Soon Sup; Jeon, Hye Won; Park, Joong Shin; Jun, Jong Kwan; Bai, Kwang Bum; Yoon, Bo Hyun; Syn, Hee Chul

Case Report

Korean Journal of Obstetrics & Gynecology 2006;49(3):667-673.
Published online March 1, 2006.

Two Cases of Pregnancies Complicated with Central Diabetes Insipidus.

Seung Ho Lee, Jin A Kim, Yong Jin Kim, Yu Kyung Lee, Kyu Ri Hwang, Soon Sup Shim, Hye Won Jeon, Joong Shin Park, Jong Kwan Jun, Kwang Bum Bai, Bo Hyun Yoon, Hee Chul Syn

¹Deparment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea. jsparkmd@snu.ac.kr
²Seoul Municipal Boramae Hospital, Seoul, Korea.

Abstract

Diabetes insipidus is an unusual cause of urinary frequency during pregnancy. It occurs in 2 to 6 per 100,000 pregnancies. It is a disorder in which the abnormal secretion, degradation, or activity of vasopressin cause hypotonic polyuria, polydipsia, and dehydration. And this syndrome appears to be associated with multiple gestations, preeclampsia, and abnormal liver function. We report two cases of pregnancies complicated with diabetes insipidus. One patient was diagnosed during pregnancy and DDAVP (L-deamino-8-d-arginine vasopressin) was used to manage diabetes insipidus. The other patient was diagnosed before pregnancy and DDAVP was not used.

Key Words: Diabetes insipidus, Pregnancy