A case of aggressive angiomyxoma of the vulva.

Park, Byung Joon; Kim, Yong Wook; Kim, Tae Eung; Maeng, Lee So

Case Report

Korean Journal of Obstetrics & Gynecology 2008;51(11):1396-1401.
Published online November 1, 2008.

A case of aggressive angiomyxoma of the vulva.

Byung Joon Park, Yong Wook Kim, Tae Eung Kim, Lee So Maeng

¹Department of Obstetrics and Gynecology, Incheon st. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea. tekim@catholic.ac.kr
²Department of Pathology, Incheon st. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.

Abstract

Aggressive angiomyxoma is an uncommon soft-tissue neoplasm which affects the pelvis and genital organs of the young female predominantly. This tumor has a high tendency of local recurrence, but it usually does not develop metastasis. Although surgical excision with wide tumor-free margins may be necessary to obtain a complete cure, some of patients experience local recurrences. Many of the tumors are estrogen receptor (ER) and progesterone receptor (PR) positive and medical therapy with gonadotropin-releasing hormone (GnRH) agonists showed to be effective in a few cases. We present a case of 29-years-old women who has aggressive angiomyxoma which was misdiagnosed as bartholin duct cyst. She was treated by wide local excision with postoperative adjuvant GnRH agonist therapy for 3 months. She is now free of disease during 9 months of follow up. We have described this case with the brief of literature.

Key Words: Aggressive angiomyxoma, Vulva