Recent trend in management of the HELLP syndrome.

Kim, Sa Jin

Clinical Trial

Korean Journal of Obstetrics & Gynecology 2009;52(5):499-507.
Published online May 1, 2009.

Recent trend in management of the HELLP syndrome.

Department of Obstetrics and Gynecology, Holy Family Hospital, The Catholic University of Korea, Bucheon, Korea. ksajin@catholic.ac.kr

Abstract

Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome is considered to be a severe form of preeclampsia. Preeclampsia is a multi system disease of pregnancy associated with a significant impact on health for both mother and fetus. Despite the voluminous literature, the diagnosis and management of this syndrome remain controversial and it is ultimately treated by delivery. Treatment of HELLP syndrome usually is supportive management, including seizure prophylaxis and blood pressure control and treatment of complications. However, several clinical trials have suggested that corticosteroids can stabilize the disease in the antepartum period and accelerate recovery after delivery. Rarely, some patients require transfusion of blood products and plasmapheresis. This articles focuses on the diagnosis, management of HELLP syndrome based on results of recent studies

Key Words: Preeclampsia, HELLP syndrome, Corticosteroid