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Obstet Gynecol Sci > Volume 53(9); 2010 > Article
Korean Journal of Obstetrics & Gynecology 2010;53(9):846-850.
DOI: https://doi.org/10.5468/kjog.2010.53.9.846    Published online September 1, 2010.
Primary malignant melanoma arising from ovarian mature cystic teratoma: A case report and literature review.
Jei Won Moon, Ji Young Kim, You Jung Shin, Mi Young Lee, Hyuck Jae Choi, Jeong Yeol Park, Joo Hyun Nam
1Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. obgyjypark@amc.seoul.kr
2Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Abstract
Primary malignant melanoma arising from the ovarian mature cystic teratoma is extremely rare, with only 31 cases have been described in the literature. It is one of the rarest forms of malignant transformation of ovarian mature cystic teratoma and usually develops unilaterally after menopause. Recently, we experienced a case of primary malignant melanoma arising from ovarian mature cystic teratoma in 71-year-old woman. The diagnosis was confirmed by positive immunohistochemical results of S-100 protein and HMB 45. Here we report the rare case with review of literature.
Key Words: Primary malignant melanoma, Ovarian mature cystic teratoma, Malignant transformation, Malignant melanoma


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