Primary malignant melanoma of the uterine cervix: A case report. |
Nae Ri Yun, Jung Woo Park, Jee Hyun Park, Suk Jin Choi, Sung Ook Hwang |
1Department Obstetrics and Gynecology, Inha University College of Medicine, Incheon, Korea. sohwang@inha.ac.kr 2Department Pathology, Inha University College of Medicine, Incheon, Korea. |
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Abstract |
After the discovery of melanocytes in the cervix in 1959, it was recognized that primary malignant melanoma of the cervix exists as a separate entity. A 74-year-old woman visited hospital for vaginal bleeding from a black colored cervical mass. The pathology of cervical punch biopsy showed a malignant melanoma with positive immnunohistochemical stainings for S100 protein and HMB-45 antibody. Abdominal radical hysterectomy with pelvic and paraaortic lymphadenectomy was performed. The final pathology was a malignant melanoma of the cervix with metastases for both external iliac lymph nodes and tumor involvement in the margin of vaginal resection. She received cisplatin based concurrent chemoradiotherapy postoperatively. But 6 months later, she received another chemotherapy with dacarbazine and cisplatin for recurrence. We report a case of a 74-year-old patient with a malignant melanoma of the uterine cervix with a brief review. |
Key Words:
Malignant melanoma, Uterine cervix, Vaginal bleeding |
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